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Procedure The study was conducted for 4 weeks, with five visits in total

[DOI] [PubMed] [Google Scholar] 40.van Zwieten R., Verhoeven A.J., Roos D

An augmented drug efflux, alteration of the molecular target, increased repair of drug-induced DNA damage, activation/suppression of signaling pathways leading to an upregulation of survival molecules and avoidance of apoptosis have been reported to be the most prominent reasons of tumor cell recalcitrance against chemotherapy (Baguley, 2010

When given at 6 mg/kg, andrographolides , the principle bioactive compounds from andrographis, demonstrated nearly 100% survival of liver cells following acetaminophen overdose (Visen 1993)